A 34-year-old construction worker in Karachi (Pakistan's largest city) has died from rabies after being bitten by his own dog more than a month ago, becoming the eighth confirmed rabies case in the southern province of Sindh this year. Medical officials say the patient received inadequate care at a government hospital, with post-exposure prophylaxis — a course of vaccine and immunoglobulin injections that can prevent the disease if given promptly — apparently mismanaged, and he died at home on April 9 after leaving Indus Hospital against medical advice. Experts warn the case exposes critical failures in rabies treatment across the province, where life-saving rabies immunoglobulin is absent from most hospitals; last year alone, 22 people died of rabies at just three Karachi hospitals, with the true provincial toll believed to be far higher due to poor disease surveillance.