Serena Williams and Carlos Alcaraz will partner for the mixed doubles at the US Open, facing Erin Routliffe and Lloyd Glasspool in the first round on Tuesday 25 August. Routliffe, alongside Gabriela Dabrowski, won the US Open women's doubles title in both 2023 and 2024, making the opening match a formidable test for the high-profile pairing. The appearance marks Williams' first match at the US Open since 2022, while Alcaraz returns to New York to defend his singles title after recovering from a wrist injury that kept him sidelined since April.