Australia periodically suffers enormous mice plagues, particularly across its grain-growing regions, in which rodent populations explode to overwhelming numbers and cause widespread destruction to crops, stored food, and residential properties. The outbreaks typically follow periods of abundant rainfall and good harvests, which provide ideal conditions for rapid breeding, with a single pair of mice capable of producing hundreds of offspring within months. The plagues pose a serious economic threat to farmers and a significant health and sanitation burden for rural communities across the country.