Pakistan's Sindh province has recorded 25 confirmed mpox cases after two more patients tested positive on Tuesday, one in Karachi and another in Khairpur, with authorities reporting nine deaths so far in 2026. Khairpur has emerged as the main hotspot, accounting for 18 of the confirmed cases, and officials say all current infections appear to stem from local transmission rather than international travel. Health authorities have faced criticism for not disclosing how the virus shifted from imported cases to community spread, nor the circumstances surrounding the deaths, which include several newborns who contracted the disease at hospital neonatal units that have since been sealed.